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diagnosis differential management hyponatremia neurology aki microscopy proteinuria renal sodium table barre classification glomerular glomerulonephritis guillain injury kidney kidneyinjury nephritic
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Syndrome Step ... /nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... #Nephrotic #Syndromes
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... suggestive of nephrotic ... sydnrome • Pigment ... #nephrology #interpretation
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... are seen in acute ... 34t5DgJ #Urinary #Casts
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... repeat testing • Acute ... proteinuria, RBC casts ... #Workup #urology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... • Interstitial nephritis ... #Diagnosis #nephrology ... #causes
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... Nephritis When ... sterile pyuria, WBC casts ... proteinuria, granular casts ... #nephrology #diagnosis
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Urinary obstruction, Nephrotoxic ... PROBLEM ~80% of AKI cases ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts ... KidneyInjury #simplified #workup
Causes of Generalized Edema - Differential Diagnosis Algorithm Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... sodium retention, Urine ... • AKI/CKD • Nephrotic ... • Sepsis • Acute ... #Causes
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• White cell casts ... infection • Hyaline casts ... disease • Granular casts ... key #diagnosis #nephrology ... #casts
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