37 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
: - RBC casts ... Causes of Hematuria ... microscopic and ... #urology #nephrology ... #renal #urine #
Granular & “Muddy Brown” Casts on Urine Microscopy
A. Finely granular cast B. slightly coarser granular cast
“Muddy Brown” Casts ... on Urine Microscopy ... appreciated at low ... #Urine #Microscopy ... #Clinical #Nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... proteinuria, RBC casts ... → Refer to Nephrology ... for renal biopsy ... #Diagnosis #Algorithm
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • Hyaline casts ... key #diagnosis #nephrology ... #casts
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Sodium 4) Serum ... Uric Acid - Low ... High Uric Acid → renal ... #nephrology #sodium ... #low #uricacid
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... (RBC casts or dysmorphic ... RBCs in urine)? ... Syndrome #Comparison #Algorithm ... #Nephrology #Diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... blood cells on urine ... microscopy. ... RBCs and/or RBC casts
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Na <20: Extra-renal ... Hypothyroidism, Low ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Microscopic exam ... • Urinary casts ... used with normal renal ... #UNa #casts #glucosuria ... #hematuria
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sterile pyuria, WBC casts ... eosinophiluria, microscopic ... hematuria, mild ... proteinuria, granular casts ... #nephrology #diagnosis