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Differential Diagnosis of Acute Kidney Injury 

#Diagnosis #Nephrology #AKI #Acute #KidneyInjury #Causes #Differential #Workup #Algorithm #Ddxof
Differential Diagnosis of Acute ... #Diagnosis #Nephrology ... #AKI #Acute #KidneyInjury ... #Causes #Differential ... #Workup #Algorithm
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
PROBLEM ~80% of AKI cases ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts ... #KidneyInjury # ... simplified #workup
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... repeat testing • Acute ... proteinuria, RBC casts ... → Refer to Nephrology ... if cause not identified
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... in a variety of acute ... #Urine #Microscopy ... #nephrology #interpretation
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Epithelial cell casts ... Obstruction • Cast ... #KidneyInjury # ... Nephrology #Differential
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
• White cell casts ... infection • Hyaline casts ... disease • Granular casts ... key #diagnosis #nephrology ... #casts
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... are seen in acute ... 34t5DgJ #Urinary #Casts
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... osmolarity If cause ... Differential #Diagnosis #nephrology ... #causes
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia is usually caused ... vast majority of cases ... 3 questions to work ... Measure urine osmolality ... Treatment #management #nephrology