14 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
sediment Microscopic ... : • Flank pain ... of glomerular hematuria ... microscopic and ... #urology #nephrology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sensitive) • AKI ... eosinophiluria, microscopic ... hematuria, mild ... tubular proteinuria, granular ... #Algorithm #nephrology
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... red - cells Non-glomerular ... also be seen if urine ... renal disease • Granular ... key #diagnosis #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
unilateral flank pain ... • Evidence of glomerular ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient have glomerular ... hematuria (RBC ... casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... hematuria. ... RBC casts in urine ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
require urgent nephrology ... IMPROVEMENT If the urine ... CONSIDER INTRINSIC CAUSES ... Assess UA w/ microscopy ... workup #diagnosis #nephrology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- Urinalysis/microscopy ... UOP/weights - Urine ... rhabdo/TLS) Causes ... #Nephrology #Diagnosis ... #Algorithm #Causes
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... Granular - May ... Muddy-brown" heme-granular ... #Differential #Microscopy ... #Diagnosis #Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... but can be seen in ... ) • Granular Casts ... #Urine #Microscopy ... #nephrology #interpretation