14 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
Causes of Polyuria ... Poorly controlled diabetes ... Diabetes Insipidus ... Hereditary, Lithium, Hypercalcemia ... #nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #medications #pharmacology ... #table #comparison
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Lower risk of hypercalcemia ... edgarvlermamd - Nephrology ... Phosphate #Binders #Table ... #Comparison #Pharmacology ... #Nephrology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Medication Guide Classes ... insulin in Type 1 Diabetes ... #Medications #pharmacology ... #comparison #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Weakness - Dark urine ... hour with goal urine ... per day until stable ... #treatment #nephrology
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Bradyarrhythmias, Some cases ... Vasopressors #Inotropes #comparison ... #table #pharmacology ... #criticalcare
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... lysis) ± Urine ... only if no clear cause ... Elimination (see Table ... Treatment #potassium #nephrology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... nephron - TTKG > 7, Urine ... Aldosterone • Diabetic ... • NSAlDs #Hyperkalemia ... IntercellularShift #Nephrology