29 results
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... stimulus to ADH • Pain ... Hypo-osmolar urine ... osmole intake #Hyponatremia ... Diagnosis #Algorithm #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... stimulus to ADH • Pain ... Hypo-osmolar urine ... osmole intake #Hyponatremia ... Diagnosis #Algorithm #Causes
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Hyponatremia - Differential ... SSRIs) Severe pain ... DrEricStrong #Hyponatremia ... Differential #Diagnosis #Table ... #Causes #Sodium
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... Decreases number of pain ... crises ( 4.5 vs ... Benefits #SickleCell #pathophysiology ... #pharmacology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Systemic effect -> Nausea ... vomiting, diarrhea, hyponatremia ... pruritus, weight gain ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Approach to Hypotonic Hyponatremia ... time you have a case ... of hypotonic hyponatremia ... volume-based algorithm Urine ... differential #diagnosis #table
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... of Excretion: Urine ... Common Uses: Trauma ... diarrhea & abdominal pain ... #Indications #Pharmacology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Treat underlying cause ... : • Causes can ... include pain, primary ... Saline: • If Urine ... SIADH #Management #hyponatremia
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Treat underlying cause ... of SIADH: Pain, ... 0.9% NS • If Urine ... Hypotension, Increased urine ... SIADH #Management #hyponatremia
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Dysfunction, Weight gain ... Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology #