9 results
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Guide Classes ... insulin dose for renal ... #Mellitus #DM2 ... #pharmacology # ... comparison #table
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Dosing Increase ... very tolerable medication ... #Renal #Dosing ... #Pharmacology #Management ... #Diabetes #DM2
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... medications, with ... kidney), which causes ... #Pharmacology # ... Medications #DM2
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... Toxicities: • Joint pains ... not definitively cause ... #Pharmacology # ... Summary #DM2 #diabetes
Lyrica (Pregabalin) 
Indications: Neuropathy (diabetic, postherpetic neuralgia, fibromyalgia, & spinal cord injury), Adjunctive therapy for partial-onset
: Neuropathy (diabetic ... partial-onset seizures Dosing ... Adjust based on renal ... drug will likely cause ... Lyrica #Pregabalin #Pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Kidney stones caused ... of Renal Epithelial ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Poorly controlled DM ... NSAIDs • ACE Inhibitors ... (Uncontrolled diabetes ... Medications 2. ... differential #diagnosis #causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Poorly controlled DM ... NSAIDs • ACE Inhibitors ... (Uncontrolled diabetes ... Medications 2. ... differential #diagnosis #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... infusion, Calcineurin inhibitors ... lysis) ± Urine ... only if no clear cause ... Elimination (see Table