19 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
- Indications and ... Pharmacology Pharmacokinetics ... of Excretion: Urine ... diarrhea & abdominal pain ... #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
severe bleeding and ... management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... • Azathioprine and ... #management #pharmacology ... #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... fever, fatigue, Nausea ... , abdominal pain ... Urticaria #diagnosis #rheumatology ... #comparison #table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... symptoms: - Muscle pain ... Weakness - Dark urine ... - Abdominal pain ... hour with goal urine
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... Rivaroxaban and ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... sle #comparison #table ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... Rule out other causes ... lower jaw Treatment ... SAPHO #Syndrome #Rheumatology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... paresthesia, abdominal pain ... hypoalbuminemia with no urine ... spacing of IVIg cures ... #rheumatology