16 results
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
Abdominal pain, nausea ... post-ingestion) - Symptom ... and metabolic acidosis ... #Toxicology #Diagnosis ... #Management #Ferrous
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... no respiratory cause ... ingestion/exposure Symptoms ... Resuscitation 2) Urine
Distal Renal Tubular Acidosis (RTA)  Type 1 

Totally scuppers the kidney's acidification mechanism. Will be
Renal Tubular Acidosis ... much easier to diagnosis ... with direct urine ... #Management #Nephrology ... #Causes #Differential
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... release Diagnosis ... improvement in symptoms ... #management #cardiology
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Stages of Iron Toxicity ... can cause an anion ... Recovery from GI symptoms ... #Toxicity #Toxicology ... #Diagnosis #Overdose
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... also includes symptoms ... LacticAcidosis #Toxicity ... #Management
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... non-arousable, decr urine ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Framework and Management ... Summary Causes ... #Management #causes ... #treatment #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... and Management ... lysis) ± Urine ... only if no clear cause ... #potassium #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Medication/Drug toxicity ... the underlying cause ... #management #neurology