1699 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... of the commonly used ... #Diabetes #Pathophysiology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
function, NSAID use ... ARB's are often used ... Nephrology #Renal #Pathophysiology
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... - Continued use ... Risky Substance Use ... - Recurrent use ... AlcoholUseDisorder #EtOH #Pathophysiology
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Corticosteroid use ... #Osteoporosis #pathophysiology
Lipoprotein Metabolism

Enterocytes release absorbed lipids the form of triglyceride-rich chylomicrons. These are acted upon by endothelial
The liver uses this ... Cholesterol #Metabolism #Pathophysiology
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
diuretics are used ... #Pathophysiology
Mean Arterial Pressure (MAP)

Mean Arterial Pressure is the average arterial pressure throughout one cycle, systole and
common method used ... Pressure #MAP #pathophysiology
Addictions: Pathogenesis

Mesolimbic Dopaminergic Pathway:
 • Dopaminergic neurons in Ventral Tegmental Area (VTA) in midbrain under continuous
motivates further drug use ... habitual compulsive use ... • Chronic drug use ... Control, Risky use ... Drug #Addiction #Pathophysiology
Biochemistry and Metabolism of Bilirubin
Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
close enough to use ... Biochemistry #Metabolism #pathophysiology
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
with loading / use ... Osteoarthritis #OA #pathophysiology