39 results
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
SHARP - Lupus Diagnosis ... D Discoid Rash ... Antibody (ANA) M Mucositis ... #IMDAMNSHARP #sle ... #diagnosis #mnemonic
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... /full triad at diagnosis ... Can also see mechanics ... #diagnosis #rheumatology
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
and Differential Diagnosis ... delta/delta) to see ... Do you need an ABG ... for acid/base, a VBG ... approximates an ABG
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
for alternate diagnoses ... Lung US, Echo, LE ... deficiency for newly diagnosed ... Sp02 88-92% • VBG ... /ABG Matthew
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... TIF1y, NXP2, Mi-2, SAE ... Inclusion Body Myositis ... MSAs #clinical #diagnosis ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... • SLE • Human ... IBD • RA • SLE ... #differential #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis ... signs #symptoms #diagnosis ... #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... muscle weakness, rash ... Inclusion Body Myositis ... #differential #diagnosis ... #comparison #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... anemia 4% - Myositis ... involvement 3% SLE-Related ... Lupusreference #SLE ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... • Transverse Myelitis ... vein thrombosis Hematologic ... Erythematosus #Diagnosis