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diagnosis differential glomerular neurology proteinuria pulmonary renal syndrome basement comparison cord disorders glomerulonephritis goodpastures hematuria management membrane membranoproliferative microscopy mpgn
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Basement Membrane Disease ... (Goodpasture's Disease ... Diagnosis: • Anti-GBM ... #Membrane #Disease
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
diseases Light ... Minimal change disease ... Amyloid RPGN • Anti-GBM ... disease • Granulomatosis ... #diseases #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... vasculitis, Behcet disease ... sclerosis • Anti-Glomerular ... Goodpasture's Disease ... ab, anti-GBM ab
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... • Drugs Glomerular ... proliferative • Anti-GBM ... Minimal change disease ... #Proteinuria #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... disease • ... wall) • Anti-GBM ... • Pauci-immune disease ... #Causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... impairment), heart disease ... diagnosis cluster, the diseases ... Nephrocalcinosis causes ... nephrotic #syndrome #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... (Dense deposit disease ... immune deposits on EM ... microangiopathy (TMA), anti-phospholipid ... Glomerulonephritis #MPGN #nephrology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
mimicry or super-antigen ... mediated disease ... Pallidum - Lyme Disease ... MCTD - Bechet disease ... AntiCRMP IgG, Anti-Hu
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Non-compressive Spinal Cord Causes ... Mycoplasma, Influenza, EBV ... Hemorrhage - Ant ... Sarcoidosis, Behcet disease ... differential #algorithm
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