11 results
diagnosis differential glomerular proteinuria pulmonary rheumatology syndrome urology vasculitis basement blood classification comparison ddxof diseases em glomerulonephritis goodpastures macroscopic membrane
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... sclerosis • Anti-Glomerular ... ab, anti-GBM ab ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... disease • ... wall) • Anti-GBM ... • Pauci-immune disease
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... • Evidence of glomerular ... for renal biopsy ... if cause not identified ... by UW IM Residency
Algorithm and Differential Diagnosis of Macroscopic Hematuria Important Historical Elements: - Painless: suggests malignancy - Painful: suggests calculi/infection - Urinalysis:
RBC’s, RBC/WBC casts ... suggest intrinsic renal ... disease - Timing ... prostatic) #Diagnosis #EM ... #IM #Urology #Hematuria
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... #Goodpastures #AntiGBM ... #diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Immunofluorescence Microscopy (IM ... Electron Microscopy (EM ... ) Haematuria/nephritis ... Amyloid RPGN • Anti-GBM ... #diseases #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... proliferative • Anti-GBM ... Minimal change disease ... #Proteinuria #Nephrology ... #Causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... Cytomegalovirus; GBM ... Nephrocalcinosis causes ... Hematuria may be ... nephrotic #syndrome #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... (Dense deposit disease ... microangiopathy (TMA), anti-phospholipid ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
multiplex • Hematuria ... pulmonary and renal ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... • Urinalysis (Renal
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