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diagnosis differential glomerular nephrotic proteinuria causes classification comparison glomerulonephritis pulmonary renal syndrome anti antigbm basement disease goodpastures hematuria membrane membranoproliferative
Spectrum of Glomerular Diseases Nephrotic - Mechanism: • Injury to podocytes • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... • Breaks in GBM ... #Diseases #differential ... spectrum #diagnosis #nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... to GBM disruption ... diabetes)) #Glomerular ... #Diseases #Nephritic ... #Proteinuria #Nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Immunofluorescence Microscopy (IM ... ) Haematuria/nephritis ... Haemolytic-uraemic syndrome Nephrotic ... RPGN • Anti-GBM ... #diseases #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... disease • ... Hereditary nephritis ... • Pauci-immune disease ... and >3.5g/day (nephrotic
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... Cytomegalovirus; GBM ... impairment), heart disease ... #Algorithm #differential ... #syndrome #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... nephropathy, lupus nephritis ... post-infectious GN Anti-Glomerular ... Differential #Diagnosis #Nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
sclerosis • Anti-Glomerular ... Goodpasture's Disease ... anti-ANCA ab, anti-GBM ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... (Dense deposit disease ... immune deposits on EM ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... (Goodpasture's Disease ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... AntiGBM #diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... • Drugs Glomerular ... proliferative • Anti-GBM ... Minimal change disease ... #Proteinuria #Nephrology
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