9 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic Syndromes ... Nephritic syndrome—due ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... • Breaks in GBM ... formation #Glomerular ... #Diseases #differential ... spectrum #diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... Immunofluorescence Microscopy (IM ... Nephrotic syndrome ... polyangiitis #glomerular ... #diseases #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... nephropathy, lupus nephritis ... post-infectious GN Anti-Glomerular ... Classification #Differential ... #Diagnosis #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... Cytomegalovirus; GBM ... = glomerular basement ... #diagnosis #glomerular ... #syndrome #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... sclerosis • Anti-Glomerular ... anti-ANCA ab, anti-GBM ... #differential # ... diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... immune deposits on EM ... anti-phospholipid syndrome ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... • Fanconi's syndrome ... • Drugs Glomerular ... #Proteinuria #Nephrology ... #Differential #
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
investigations depending on clinical ... ANCA, ANA, Anti-GBM ... • Interstitial nephritis ... • Cardio-renal syndrome ... #Diagnosis #nephrology