14 results
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Diagnosis Framework ... : Microscopic Polyangiitis ... Churg Strauss) Anti-GBM ... #diagnosis #nephrology ... #causes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
of cases) 2 ... Vasculitis: • Microscopic ... + 90% • Anti-GBM ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... Disease-specific testing: anti-ANCA ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... #diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Henoch-SchonIein Purpura Anti-GBM ... Limited to Kidney: Anti-GBM ... pulmonary involvement: Anti-GBM ... #rheumatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Diagnosis Baseline ... dipstick, urine microscopy ... , ANA, Anti-GBM, ... #Diagnosis #nephrology ... #causes
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Diagnosis Framework ... Vasculitis • GN: ANCA ... , Anti-GBM, C3/C4 ... #Diagnosis #nephrology ... #causes #algorithm
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential ... Diagnosis Algorithm ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
): • Microscopic ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... Dx: GPA, EGPA, microscopic ... #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... function test, ANA ... When do you do a BM ... #Diagnosis #Causes ... #Workup #hematology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - Differential ... Diagnosis Algorithm ... Glomerulonephritis • Anti-GBM ... polyangiitis /microscopic ... #KidneyInjury #Nephrology