12 results
diagnosis differential renal causes pulmonary algorithm classification glomerulonephritis hematuria rheumatology vasculitis acute aki antigbm basement blood comparison disease giomeruiar goodpastures
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... (IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... #diseases #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... , proteinuria) ... post-infectious GN Anti-Glomerular ... Differential #Diagnosis #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
cells on urine microscopy ... disease • ... wall) • Anti-GBM ... • Pauci-immune disease ... nephrotic range) proteinuria
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Nephrology #Differential
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... • Urinalysis (proteinuria ... ab, anti-GBM ab ... differential #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Acute Kidney Injury ... • Vascular • Glomerular ... Immune-complex disease ... , Anti-GBM • Tubular ... Differential #Diagnosis #nephrology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Immune mediated injury ... basement membrane disease ... Brown urine - Proteinuria ... disease Renal ... causes #urology #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... directed against the glomerular ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... AntiGBM #diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
RBC casts, +/- proteinuria ... formation along glomerular ... (Dense deposit disease ... microangiopathy (TMA), anti-phospholipid ... Glomerulonephritis #MPGN #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... quantify renal injury ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... hypercellular glomeruli
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