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differential rheumatology vasculitis acute aki anca causes injury kidney algorithm ana antibodies antibody antigbm antineutrophil antinuclear associated basement canca classification
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... #diseases #nephrology ... comparison #table #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... for Pulmonary Renal ... sclerosis • Anti-Glomerular ... ab, anti-GBM ab ... #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
- Differential Diagnosis ... Framework PRE-Renal ... • Vascular • Glomerular ... , Anti-GBM • Tubular ... #nephrology
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
classified into pre-renal ... and interstitial disease ... GBM, Glomerular ... #Diagnosis #AKI ... Causes #Sites #Nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... diseases with pulmonary ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... #Pulmonary #Renal
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Vasculitis: • Microscopic ... polyangiitis without renal ... ANCA+ 90% • Anti-GBM ... disease - MPO>PR3 ... Antineutrophil #antibodies #diagnosis
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... hemorrhage Diagnosis ... : • Anti-GBM antibodies ... weeks By Tess Litchman ... #nephrology #pulmonary
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis without renal ... >MPO Microscopic ... Renal-limited ... Anti-GBM disease ... #Diagnosis #Rheumatology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and renal abnormalities ... -ANCA): • Microscopic ... glomerulonephritis) • Anti-GBM ... Dx: GPA, EGPA, microscopic ... • Urinalysis (Renal
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