21 results
diagnosis differential neurology lupus pulmonary sle syndrome vasculitis classification dermatology erythematosus hematology hemophagocytic hlh lymphohistiocytosis renal summary systemic anca antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Vasculitis: • Microscopic ... + 90% • Anti-GBM ... Jcortesizaguirr #ANA ... antibodies #diagnosis #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... testing: anti-ANCA ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... differential #diagnosis #nephrology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
> - Anti-ENA ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis, causes ... and management ... neuropathy Treatment ... with refractory disease ... Cryoglobulinemia #Vasculitis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... ) - Anti-ENA ... Discontinuation of causal ... Evolution: Chronic disease ... comparison #table #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause ... differential #diagnosis #management ... #treatment
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
- but 5% have anti—muscle-specific ... More likely to cause ... Hospital of Baltimore IM ... Gravis #diagnosis #management ... #neurology #treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... #rheumatology # ... cerebritis #diagnosis #management ... #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... often causes arthritis ... glomerulonephritis) • Anti-GBM ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
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