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differential algorithm pathology electronmicroscopy glomerulus pulmonary renal rheumatology sem vasculitis acute aki antigbm basement classification comparison disease diseases glomerulonephritis goodpastures
Glomerular Tuft on Electron Microscopy This eyeSCANdy image shows acellular scanning EM of a normal glomerular tuft
Glomerular Tuft ... on Electron Microscopy ... of a normal glomerular ... #glomerular #tuft ... #nephrology #pathology
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 Glomerular Tuft on Electron Microscopy This eyeSCANdy image shows acellular scanning EM of a normal glomerular tuft
Glomerular Tuft ... on Electron Microscopy ... of a normal glomerular ... #glomerular #tuft ... #nephrology #pathology
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 Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... (IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... polyangiitis #glomerular
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular ... wall) • Anti-GBM
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... directed against the glomerular ... : • Anti-GBM antibodies ... #GIomeruIar #Basement ... #nephrology #pulmonary
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... ab, anti-GBM ab ... #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... microangiopathy (TMA), anti-phospholipid ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... dipstick, urine microscopy ... investigations depending on clinical ... Vasculits: ANCA, ANA, Anti-GBM ... #nephrology #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... Vasculitis - Skin, glomeruli ... : - Kidneys: glomerular
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