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diagnosis differential causes algorithm acute aki renal rheumatology vasculitis antigbm basement classification comparison disease diseases giomeruiar glomerular glomerulonephritis goodpastures injury
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... polyangiitis, Microscopic ... ab, anti-GBM ab ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
diseases Light Microscopy ... (IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... glomerular #diseases #nephrology
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Wegener's) • P-ANCA: Microscopic ... Churg Strauss) Anti-GBM ... differential #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... polyangiitis) Anti-basement ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... FINDINGS: • U/A: microscopic
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Vasculits: ANCA, ANA, Anti-GBM ... , Anti-ds-DNA, C3 ... Differential #Diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Glomerulonephritis • Anti-GBM ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
disorder (Cardiac, pulmonary ... Coxsackie, HIV, CMV, EBV ... /SSA, anti-La/SSB ... , anti-Sm, and anti-RNP ... Differential #Diagnosis #neurology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... AntiGBM #diagnosis #nephrology ... #pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... PR3-ANCA): • Microscopic ... glomerulonephritis) • Anti-GBM ... Urticarial Vasculitis (anti-C1q ... Dx: GPA, EGPA, microscopic
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