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diagnosis differential acute aki rheumatology diseases glomerular injury kidney proteinuria pulmonary vasculitis ana anca antibodies antibody antineutrophil antinuclear classification comparison
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... polyangiitis, Microscopic ... anti-ANCA ab, anti-GBM ... biopsy By Tess Litchman ... #diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... dipstick, urine microscopy ... ANCA, ANA, Anti-GBM ... Differential #Diagnosis #nephrology ... #causes
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Framework Pre-Renal ... Abdominal Compartment Syndrome ... GN: ANCA, Anti-GBM ... Differential #Diagnosis #nephrology ... #causes #algorithm
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... • Hepatorenal syndromes ... Glomerulonephritis • Anti-GBM ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Nephrotic syndrome ... RPGN • Anti-GBM ... glomerular #diseases #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause ... FINDINGS: • U/A: microscopic
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
• Sjögren syndrome ... Vasculitis: • Microscopic ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... + 90% • Anti-GBM
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... Nephrocalcinosis causes ... #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... PR3-ANCA): • Microscopic ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... • Urinalysis (Renal
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