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differential acute aki algorithm pulmonary rheumatology injury kidney vasculitis ana antibodies antibody antineutrophil antinuclear basement classification disease diseases giomeruiar glomerulonephritis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Basement Membrane ... Disease-specific testing: anti-ANCA ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... #nephrology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Vasculitis: • Microscopic ... polyangiitis without renal ... + 30-60% • Renal-limited ... + 90% • Anti-GBM ... Antineutrophil #antibodies #diagnosis
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
- Differential Diagnosis ... : Microscopic Polyangiitis ... Churg Strauss) Anti-GBM ... #differential #diagnosis ... #nephrology #causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... dipstick, urine microscopy ... Glomerulonephritis / Vasculits: ANCA ... , ANA, Anti-GBM, ... #nephrology #causes
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
- Differential Diagnosis ... Vasculitis • GN: ANCA ... , Anti-GBM, C3/C4 ... #Differential #Diagnosis ... #nephrology #causes
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... membrane: Goodpasture ... Auto-antibodies: ANCA ... antibody, Anti-GBM ... usually low in anti-GBM
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
hemorrhage Diagnosis ... : • Anti-GBM antibodies ... weeks By Tess Litchman ... #Goodpastures #AntiGBM ... #diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
- Differential Diagnosis ... at least 50% Renal ... Glomerulonephritis • Anti-GBM ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... ): • Microscopic ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... • Urinalysis (Renal
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... )): Microscopic ... tract, and often causes ... abdominal pain and GN Anti-GBM
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