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diagnosis differential algorithm pulmonary renal acute aki rheumatology vasculitis antigbm basement classification comparison disease diseases giomeruiar glomerular goodpastures hematuria injury
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Glomerulonephritis ... Wegener's) • P-ANCA: Microscopic ... Churg Strauss) Anti-GBM ... differential #diagnosis #nephrology ... #causes
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... cells on urine microscopy ... wall) • Anti-GBM ... with polyangiitis/microscopic ... Diagnosis #Algorithm #Causes
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... polyangiitis, Microscopic ... ab, anti-GBM ab ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... and signs • Glomerulonephritis ... Vasculits: ANCA, ANA, Anti-GBM ... Differential #Diagnosis #nephrology ... #causes
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Rapidly Progressive Glomerulonephritis ... • Anti-GBM antibodies ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
diseases Light Microscopy ... (IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... glomerular #diseases #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... dysmorphic RBC, RBC casts ... immune deposits on EM ... microangiopathy (TMA), anti-phospholipid ... #MPGN #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology ... Diagnosis #Algorithm #Causes
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... renal failure (glomerulonephritis ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... tract, and often causes ... ) • Anti-GBM - ... Urticarial Vasculitis (anti-C1q ... Dx: GPA, EGPA, microscopic
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