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management differential algorithm abnormal aptt prolonged pt syndrome workup acidosis acs anesthesia anesthesiology angina arterial arteritis bleeding bradycardia bruising calculi
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... ) • Advanced Liver ... Autoimmune disorders (e.g ... #comparison #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Syndrome, Ischemic Liver ... intravascular coagulation ... and other causes ... pathophysiology #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #diagnosis #differential ... #hematology #coagulation
Treatment of Stable Narrow-Complex Tachycardia Regular Rhythm: • Attempt vagal maneuvers • Give adenosine 6 milligrams IV
Treatment of Stable ... Control rate (e.g ... Treat underlying cause ... Control rate (e.g ... #management #cardiology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... • Reduced liver ... #hematology #coagulation
Acute Coronary Syndrome (ACS) Definitions - Stable Angina, Unstable Angina, NSTEMI, STEMI 1 STABLE ANGINA - Angina
thrombus formation causes ... partial occlusion ... is reflected by ECG ... #Diagnosis #Cardiology ... Text: The Only EKG
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... of information (e.g ... non-essential drug/HDS treatments ... for alternative causes ... vascular disorder (e.g
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Cardiac Stress Testing Exercise: • Everyone who can exercise should! • They must be able to raise
• They must be able ... 85% of predicted value ... production to cause ... : EKG ($), ECHO ... Stress #Testing #cardiology
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