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hematology management differential neurology oncology syndrome algorithm clinical workup disorders leukemia radiology aplastic chronic classification cll lymphocytic mds myelodysplastic pathophysiology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Script Signs and symptoms ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #diagnosis #management ... #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... effect following treatment ... Iron deficiency anemia ... #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... immune-complex hemolytic anemia ... Prosthetic heart valves ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... priapism • Lab values ... sudden death • Lab values ... Syndrome #TLS #diagnosis ... #management #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... changes), high MCV anemia ... #Differential #Diagnosis ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... of anemia or thrombocytopenia ... marrow failure with anemia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology Imaging Findings: • Os trigonum which has marrow
Trigonum) Syndrome - MSK ... posterolateral talus ... Case description ... flexion but no symptoms ... #msk
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... focal lesions on MRI ... Causes of false- ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
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