12 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... WBC >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
- Pathophysiology ... Ill-appearing, vital sign ... #Diagnosis #Dermatology ... Targetoid #Algorithm #Differential ... #Ddxof
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH, Evans Syndrome ... #Hemolysis #Differential ... #Diagnosis #hematology
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
you perform age adjusted ... Patient age 88 = age adjusted ... Ddimer #dimer #pathophysiology ... #hematology #differential ... diagnosis #age #adjusted
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... significant portal HTN Signs ... and hepatorenal syndrome ... • Budd Chiari syndrome ... Diagnosis #causes #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... • Nephrotic Syndrome ... from prosthetic valves ... Venous #Arterial #pathophysiology ... #hematology #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome ... diagnosis #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... bile ducts Differential ... diagnosis #workup #hepatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... appreciate the value ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential