36 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Pancreatitis - Elevated Liver ... - Budd Chiari Syndrome ... Complications #pathophysiology ... #signs #symptoms
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology ... #pathophysiology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... thin smear • Signs ... Liver biopsy • ... biopsy • Lab values ... supporting hematologic
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... #Diagnosis #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... significant portal HTN Signs ... and hepatorenal syndrome ... • Budd Chiari syndrome ... sarcoidosis) • Liver
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... • Nephrotic Syndrome ... , Ischemic Liver ... Venous #Arterial #pathophysiology ... #hematology #differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology ... #Differential #
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... /Symptoms/Exam findings ... #dermatology