14 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Highest • Bone • Liver ... Most common symptoms ... #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
• R value = (ALT ... + ULN ALT) / (alkaline ... phosphatase + ULN alkaline ... Transaminitis #diagnosis #differential ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... compared with alkaline ... disproportionate increase in alkaline ... #Diagnosis #hepatology ... #algorithm #Transaminitis
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
See the lab values ... table for supplemental ... #Diagnosis #Algorithm ... #Differential # ... Peds #Pediatrics #Table
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... suspicious clinical symptoms ... ALP, alkaline phosphatase ... #Hepatology #Liver ... #Enzymes #Differential
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Metabolism A table ... of lab values compiled ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... Peds #Pediatrics #Table
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... Returning Traveler’ algorithm ... Liver biopsy • ... biopsy • Lab values ... supporting hematologic
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... synthesized in: liver ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Hyophosphatasia #hepatology