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diagnosis hepatology lfts enzymes hepatocellular transaminitis abnormal alp arterial biliary cholangitis cholestatic cirrhosis dili drug elevation embolism gastroenterology hepatitis idiosyncratic
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Injury ... • R value = (ALT ... + ULN ALT) / (alkaline ... Transaminitis #diagnosis #differential ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... #Injury #Differential ... #algorithm #Transaminitis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Highest • Bone • Liver ... Most common symptoms ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... Calculate R-Value ... #differential # ... gastroenterology #algorithm ... gastroenterology #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... suspicious clinical symptoms ... ALP, alkaline phosphatase ... #Hepatology #Liver ... #Enzymes #Differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... PBC Labs: • Alkaline ... or higher • Liver ... bile ducts Differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Syndrome, Ischemic Liver ... Vasculitis • Injury ... Venous #Arterial #pathophysiology ... #hematology #differential
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