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diagnosis differential algorithm nephrotic renal causes classification glomerulonephritis management nephritic blood gitelman hematuria hypokalemia interpretation pulmonary sodium syndromes testing treatment
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... Proteinuria often ... diabetes)) #Glomerular ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... the patient have glomerular ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... • Evidence of glomerular ... bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
(Negative urine ... • Fanconi's syndrome ... • Drugs Glomerular ... ) - Active urine ... #Nephrology #Differential
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
disease 24-hour urine ... Spot PC (protein ... Serum or urine for ... #testing #workup ... nephrotic #nephritic #nephrology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... - Proteinuria ... • Nutcracker syndrome ... #nephrology #renal
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
proteinuria. ... hemolytic-uremic syndrome ... arbitrarily defined as urine ... because nephritic urine ... #syndrome #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
disease 1) 24-hour urine ... Spot PC (protein ... Serum or urine for ... #workup #diagnosis ... initial #testing #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
function over a short ... with evidence of glomerular ... disease (hematuria, proteinuria ... immune deposits in glomeruli ... Differential #Diagnosis #Nephrology
Urine Specific Gravity - Interpretation Specific Gravity = Density of urine / Density of water SG close to
Urine Specific Gravity ... Gravity = Density of urine ... Dehydration • SIADH (syndrome ... Glycosuria • Proteinuria ... #differential #nephrology
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