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diagnosis differential algorithm nephrotic causes nephritic blood classification gitelman glomerulonephritis hematuria hypokalemia management pulmonary syndromes testing urology abg acid acidbase
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... bleeding (proteinuria ... → Refer to Nephrology ... for renal biopsy ... cystoscopy • Refer to Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... Proteinuria often ... diabetes)) #Glomerular ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... the patient have glomerular ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
(Negative urine ... • Fanconi's syndrome ... • Drugs Glomerular ... ) - Active urine ... #Nephrology #Differential
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... - Proteinuria ... • Nutcracker syndrome ... #nephrology #renal
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Abdominal compartment syndrome ... syndrome: troponin ... #Injury #AKI #Workup ... Differential #Diagnosis #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
disease 24-hour urine ... Spot PC (protein ... Serum or urine for ... #testing #workup ... nephrotic #nephritic #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... formation along glomerular ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... sclerosis • Anti-Glomerular ... • Urinalysis (proteinuria ... #diagnosis #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
proteinuria. ... hemolytic-uremic syndrome ... arbitrarily defined as urine ... because nephritic urine ... #syndrome #nephrology
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