79 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Drug-induced SLE ... Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... diagnosis #table #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... erythematosus (SLE ... connective tissue disease ... ), Sjogren's Syndrome ... ANA #patterns #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... Shrinking lung syndrome ... , Behçet's syndrome ... differential #diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
Connective tissue disease-associated ... interstitial lung diseases ... PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... Table #Pulmonary #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
PIP Involvement, Spares ... Tunnel, Sicca Syndrome ... Scleritis, Heart Disease ... Nodules, Pulmonary Disease ... RA #diagnosis #rheumatology
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... complex storage diseases ... connections and pathophysiology ... See the lab values ... MetabolicEmergency #Genetics #Pathophysiology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... erythematosus (SLE ... ), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... infection • Lyme disease ... IBD • RA • SLE ... Antiphospholipid-antibody syndrome ... differential #diagnosis #rheumatology