37 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... : • Pathophysiology ... sudden death • Lab values ... TLS #diagnosis #management
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
B1 (Thiamine) Deficiency ... Diagnosis and Management ... treatment can improve symptoms ... development of Korsakoff syndrome ... #Diagnosis #Management
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
(IBS) - Pathophysiology ... Diagnosis and Management ... factors affecting symptom ... #Pathophysiology ... #Diagnosis #Management
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... fractures • Short ... #genetics #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Protein S deficiency ... • Nephrotic Syndrome ... from prosthetic valves ... Infected cardiac valves ... Venous #Arterial #pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... improvement in symptoms ... alissa_shega #iron #deficiency ... heartfailure #diagnosis #management
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... Hypo-Mg2+ • Vitamin deficiency ... overload) Other Symptoms ... • Vitamin D deficiency ... Differential #Diagnosis #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... : • GH deficiency ... : - Short ... endocrinology #pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... Causes of Thiamine Deficiency ... - Refeeding syndrome ... : - Impaired short-term ... beriberi #nutrition #pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
with vitamin A deficiency ... conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... diagnosis #signs #symptoms