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differential hepatology liver lfts transaminitis causes gastroenterology hepatitis management syndrome abnormal acidosis ascites behcet bowel chemistry classification dermatology dili drug
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... ALP ≥ 2x ULN R Value ... Transaminitis #diagnosis ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Bilirubin - +/- elevation ... extrahepatic source - Tests ... #algorithm #hepatology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... Test for the respective ... biopsy • Lab values ... supporting hematologic ... #diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... symptoms of liver disease ... Calculate R-Value ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... → liver test abnormalities ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... #hepatology #algorithm
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
algorithm. ... magnitude of enzyme elevation ... alcohol-related liver disease ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... hallmark for the disease ... If the value is ... Mild-to-moderate elevation ... #Workup #Hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary Use a positive diagnostic strategy with minimal testing.
and Workup Summary ... Criteria - Recurrent abdominal ... cultures, but test ... Rule out celiac disease ... Balloon Expulsion Test
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... of cholestatic disease ... Alcoholic liver disease ... liver #chemistry #diagnosis ... #differential #Hepatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
to local skin injury ... Positive pathergy test ... is a skin prick test ... • Nonsurgical abdominal ... signs #symptoms #rheumatology
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