61 results
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
of Severe Acute Liver ... Injury - Ichemic ... Wilson disease ... #Differential #Hepatology ... #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... → liver test abnormalities ... Infections: Hepatitis ... HELLP, Celiac disease ... #Diagnosis #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... injury) • Ischemic ... #Function #Tests ... #hepatology #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... #Injury #Differential ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
disease, liver ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... #Patterns #Liver ... #Injury #hepatology ... #differential #diagnosis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... • R value = (ALT ... Transaminitis #diagnosis ... #differential #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... ALP ≥ 2x ULN R Value ... Hepatocellular injury ... Transaminitis #diagnosis ... #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... >1.5, and both values ... ) or metabolic liver ... atypical laboratory tests ... #Diagnosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... extrahepatic source - Tests ... #injury #hepatitis ... #algorithm #hepatology