27 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Coagulation Failure Infections ... Alcohol-Associated ... Failure #Cirrhosis #Hepatology ... #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
risk-stratification • Risks: infection ... transformation to acute ... only curative treatment ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... Symptomatic anemia Diagnosis ... progress to MDS or acute ... #management #treatment ... #hematology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
and Management ... neutropenia (performs best ... septated hyphae, acute ... this morphology Treatment ... #Management #treatment
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... >20) - Obtain abdominal ... - Screen for infection ... #Algorithm #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... presents as an acute ... : • Infection ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... sudden death • Lab values ... Syndrome #TLS #diagnosis ... #management #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... Hepatocellular: Viral infections ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... #Algorithm #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Rare: DAH, acute ... : Infection (sepsis ... Renal Failure Treatment ... #management #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
skin necrosis (at injection ... approach for post-test ... : Confirmatory test ... #Management #Treatment ... #Hematology #HemeOnc