20 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Calculate R-Value ... #DILI #Drug #induced ... gastroenterology #hepatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Initial screening test ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... 60-70%) & drug-induced ... clinically suspected, tests ... erythematosus #diagnosis ... #rheumatology #
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and initial management ... HIT laboratory tests ... #Diagnosis #Management ... #Hematology #HIT ... #Heparin #Induced
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... approach for post-test ... : Confirmatory test ... #HIT #Heparin #Induced ... #Hematology #HemeOnc
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Antihistone: Drug induced ... Erythematosus #Diagnosis
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... >1.5, and both values ... Possible drug-induced ... atypical laboratory tests ... Hepatitis #AH #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SJIA], systemic lupus ... Sepsis • Drug-induced ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... >1.5, and both values ... Possible drug-induced ... atypical laboratory tests ... #Hepatology #AIH