10 results
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Age-appropriate cancer ... - No other workup ... Age-appropriate cancer ... #hematology #diagnosis ... #algorithm #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... sudden death • Lab values ... #TLS #diagnosis ... #management #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
- Differential Diagnosis ... Algorithm Appropriately ... , Acute Respiratory ... (MM, lymphoma, cancer ... #phosphorus #workup
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... obstruction, HELLP Syndrome ... Pancreatic Pseudocyst, Cancer ... #Differential #Diagnosis ... #algorithm #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... microglobulin Treatment ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
↑ Can develop leukostasis ... syndrome: CNS manifestations ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... #Oncology #Diagnosis
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... (Acute Febrile ... Excellent response to treatment ... Abnormal laboratory values
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
current treatment ... algorithm 2018. ... clonal evolution to acute ... median age at diagnosis ... #algorithm #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... changes (POEMS syndrome ... ovarian tumors, lung cancers ... inflammation (acute ... #differential #diagnosis