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diagnosis differential rheumatology vasculitis erythematosus lupus sle systemic anemia causes champs clinicopathology criteria cryoglobulinemia cryoglobulins disorders eularacr gammopathy glomerulonephritis hypocomplementemia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... Hypocomplementemia #Low ... #Complement #CHAMPS ... #differential #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... pericarditis • Hematologic ... > 0.5 g/24 hr, Class ... lupus nephritis, Class ... anticoagulant • Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... differential #diagnosis #algorithm ... #rheumatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... Low Mean Corpuscular ... #Anemia #MCV #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... factor level • Low ... serum C4 complement ... #classification ... #rheumatology #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... B-Cell ~90% • Low ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... Kikuchi disease • Type-I ... , lymphopenia, low
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... against MPO • Complement ... (Low levels mixed ... differential #diagnosis #rheumatology ... #classification
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
meet criteria for hematologic ... guide subtype classification ... Damages Kidneys • Low ... tubulopathy) - Complement ... vasculitis Types
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
should use this algorithm ... risk of smallpox –low ... specimens from low ... The type of specimen ... all HIGH RISK CASES
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