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management hematology oncology infectiousdiseases neurology differential algorithm barre cppd disease guillain hemophagocytic hiv hlh lymphohistiocytosis mds myelodysplastic parasite thrombocytopenia workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... microglobulin Treatment ... • Richter’s Syndrome ... ’s lymphoma or acute ... leukemia • Sezary syndrome
Leishmaniasis Life Cycle 1) Sandfly takes a blood meal (injects promastigote stage into the skin) Human Stages: 2) Promastigotes
of parasitized cell ... Divide in the gut ... Leishmaniasis #LifeCycle ... #diagnosis #pathophysiology ... infectiousdiseases #cdc
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... virus: CMV, HSV, Varicella ... Effusions: - Gout ... - Pseudo gout ... - Acute rheumatic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... • Induce blast cell ... Renal Failure Treatment
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... culture used to diagnose ... • Metabolic syndrome ... #Comparison #rheumatology ... #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - ACS, AKI, acute ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
on ABx) → Acute ... Perforation) Pathophysiology ... - produced by all ... Treatment Guideline ... #management #treatment
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Gout - Diagnosis ... sex • Metabolic syndrome ... cortical bone Treatment ... gout treatment; ... #treatment #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Responsive to Treatment ... Treated Like Acute ... Classification #pathophysiology ... #Hematology #Diagnosis
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