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management differential syndrome aids causes hematology hemophagocytic hiv hlh infections infectiousdiseases lymphohistiocytosis associated behcet cauda caudaequina cerebritis coagulation dementia dic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... permeability Diagnosis ... Erythematosus #SLE #CNS ... #neurology #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
- Differential Diagnosis ... cells per μL • Diagnosis ... Antimicrobial treatment ... status, and focal neurologic ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... and infects the CNS ... Diagnosis: MRI ... Treatment: • HAART ... dementia #AIDS #Neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
of a previously diagnosed ... IRIS: Generally Diagnosis ... No specific diagnostic ... pleural effusions, CNS ... ulceration • Varicella
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... : • Serology for
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
equina syndrome (CES ... Differential Diagnosis ... axial T1 and T2 Treatment ... #differential #diagnosis ... #causes #neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
/aggregate) of CD4 ... nervous system (CNS ... • 8%-27% for CNS ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
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