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hematology management infectiousdiseases oncology differential workup causes parasite syndrome algorithm chronic disorders lymphocytic 1 american apml arthritis bandemia barre cdi
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... Lymphocytosis on CBC ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... #oncology #hematology ... #hemeonc #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... Chronic Myelogenous Leukemia ... effect following treatment ... Algorithm #Causes #Hematology
Malaria - Plasmodium Life Cycle 1) Mosquito takes a blood meal (injects sporozoites) Human Liver Stages 2) Infected liver
Infected liver cell ... Malaria #Plasmodium #lifecycle ... #diagnosis #pathophysiology ... infectiousdiseases #cdc
Leishmaniasis Life Cycle 1) Sandfly takes a blood meal (injects promastigote stage into the skin) Human Stages: 2) Promastigotes
of parasitized cell ... Leishmaniasis #LifeCycle ... #diagnosis #pathophysiology ... infectiousdiseases #cdc
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... Tissue damage • Leukemia ... #differential #diagnosis ... #CBC #hematology ... #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Responsive to Treatment ... Treated Like Acute Leukemias ... Classification #pathophysiology ... #Hematology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... decreased PLT count: CBC ... (CVID, WAS), (neurologic ... not required in all ... #Differential #Diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
pain, Fever, ↑WBC ... Perforation) Pathophysiology ... - produced by all ... Treatment Guideline ... #management #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... • Induce blast cell ... Renal Failure Treatment ... #management #hematology
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