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diagnosis transaminitis causes hepatitis hepatocellular abscess acute chemistry children cholestatic dili drug effusion enzymes function gastroenterology idiosyncratic induced interpretation management
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... more specific for hepatic ... Transaminitis #diagnosis #differential ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... injury) • Ischemic ... ) • Non-hepatic ... Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... #Injury #Differential ... #LFTs #hepatitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... Chronic - ongoing ↑ LFTs ... #differential # ... gastroenterology #algorithm ... gastroenterology #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Vasculature • Hepatic ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Pleural Effusion - Differential ... Diagnosis Algorithm ... Diaphragmatic: • Hepatic ... • Postcardiac injury ... #Hepatology #causes
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Pyogenic liver abscess ... from contiguous focus ... through: - Hepatic ... children #peds #differential ... #diagnosis #hepatology
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