16 results
diagnosis management differential lupus oncology sle erythematosus hemophagocytic hlh lymphohistiocytosis summary thrombocytosis aplastic arteritis classification cll common comparison cvid druginduced
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... : • Acute or Chronic ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Inflammation • Cancer ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... • Infections: Chronic ... #hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... • Epstein-Barr Virus ... Idiopathic - Chronic ... Destruction • Systemic ... #Causes #Hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... • Evolution: Chronic ... Management #Summary #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • Epstein-Barr virus ... Treatment: ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Orange or Hep C Clinical ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... B-LNH), solid cancers ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... complaints- anemia ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology
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