10 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and ... of Sickle Cell Crises ... Clinical Manifestations ... Diagnosis #Management #Hematology ... Manifestations #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... management of SLE • Evolution ... : Chronic disease
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... : Chronic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... autoantibodies that will cause ... (for secondary APS ... CNS #neurology #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Autoimmune Vasculitis (lupus ... Rash: - ITP - APLS ... deficiency Work ... #Causes #dermatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus ... • Autoimmune diseases ... inhibitors under evaluation
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Hypercoagulable Workup ... - 1 or more clinical ... maternal chromosomal causes ... excluded Testing: • Lupus ... #hematology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Preoperative Risk Evaluation ... to perform own ADLs ... event, follow ACC algorithm ... Change in clinical ... perioperative #Risk #Evaluation
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... • Immunologic Workup ... Discontinuation of causal ... cutaneous-DIL • Evolution ... #DIL #rheumatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... • Caused by splanchnic ... Diagnosis (Clinical ... e.g., alcohol, virus ... liver transplant evaluation