49 results
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
an identifiable cause ... The cause is unknown ... associated with viral infections ... #Bells #Palsy #neurology ... #anatomy #pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... response preceding infection ... COVID 19 - Zika virus ... Syndrome #diagnosis #management ... #treatment #neurology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... invasion via URT infection ... and hematologic infection ... widespread infection ... peds #pediatrics #pathophysiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... the underlying pathophysiology ... Syndrome #diagnosis #management ... #neurology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Chemotherapy • Infectious ... Inflammatory/AI: CIDP, Guillain-Barre ... differential #diagnosis #causes ... #neurology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... ng/mL (absolute ID ... 20% (functional ID ... heartfailure #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Triggering factor (infection ... +++: Virus (EBV, ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
present in 15% of cases ... status, and focal neurologic ... Demyelinating disease caused ... confusion, and focal neurologic ... InfectiousDiseases #Neurology
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
Hepatitis B Virus ... Serology and Interpretation ... (about 10% of cases ... less commonly, infection ... HepatitisB #HBV #Serology
Cytomegalovirus (CMV) in HIV-AIDS Patients
Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family.
CMV infection: virus isolation or detection
double-stranded DNA virus ... CMV infection: virus ... 50 or less: • Neurologic ... Retinitis (Most common cause ... • Endocrine: Infectious