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syndrome barre differential guillain nephrology rheumatology acute anemia aplastic apml cancer cerebritis classification cns differentiation erythematosus gbs guillainbarre hemophagocytic hepatology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Kidney Injury (AKI ... change disease • Hematologic ... malignancies Treatment ... #Cancer #Oncology ... #Differential #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... fever - ACS, AKI ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... #management #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Infections+++: Virus ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• Epstein-Barr virus ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... COVID 19 - Zika virus ... Guillain-Barre Diagnosis ... #management #treatment ... #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
bulbar muscles DIAGNOSIS ... the underlying pathophysiology ... and cauda equina TREATMENT ... Barre #Syndrome #diagnosis ... #management #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... Transverse Myelitis Treatment ... #management #neurology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... Treatment Overview ... e.g., alcohol, virus ... Hepatorenal #Syndrome #Hepatology ... #Nephrology #Diagnosis
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