21 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... to explain symptoms ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... Antimicrobial treatment ... Herpes Simplex Virus ... • JC-virus PCR ... differential #diagnosis #AIDS
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
invade URT & via hematologic ... hemorrhagic rash; symptoms ... causes CNS and hematologic ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... be present: • AIDS ... Confusion, visual symptoms ... uveitis, Extraocular symptoms ... IRIS with severe symptoms
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... COVID 19 - Zika virus ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
adenomas that require treatment ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... Renal Failure Treatment ... diagnosis #management #hematology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... • Depressive symptoms ... Treatment: • HAART ... treatment • Cognitive ... disorder #dementia #AIDS