30 results
Cardiac Amyloid - Diagnosis, Signs, Symptoms and Management

Clinical Presentation
- exertional dyspnea
- peripheral edema
- exertional syncope
- peripheral
Cardiac Amyloid ... - Diagnosis, Signs ... , Symptoms and Management ... AL) - Kussmaul sign ... #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
trabecular thinning -> Avascular ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... • Cardiac: myocardial ... myositis overlap • Vascular ... rheumatology #diagnosis #signs ... #workup
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
MeralgiaParesthetica #MSK ... #pathophysiology ... #differential # ... diagnosis #signs ... #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
to myosin and cardiac ... Pancarditis and valvular ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Cardiovascular disease: • Cardiac ... arrhythmia • Valvular ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs ... Consider cardiac
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Pulmonary Edema - Cardiac ... - Tetany - Cardiac ... Constipation - MSK ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... lethargy, hematuria, cardiac ... with tetany or cardiac ... TLS #diagnosis #management
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
• Compensatory muscular ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis ... #msk